Antimicrobial drug discovery : (Record no. 313344)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 07204nam a2200901 i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20123306539 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | CtWfDGI |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20201203121120.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr zn||||uuuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130731t20122012enkad ob 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9781845939434 (alk. paper) |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | CtWfDGI |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | CtWfDGI |
| 050 14 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM267 |
| Item number | .A554 2012eb |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.7/92 |
| Edition number | 23 |
| 245 00 - TITLE STATEMENT | |
| Title | Antimicrobial drug discovery : |
| Remainder of title | emerging strategies / |
| Statement of responsibility, etc | edited by George Tegos, University of New Mexico, Department of Pathology, Center for Molecular Discovery, University of New Mexico Health Sciences, Albuquerque, USA and Eleftherios Mylonakis, Harvard Medical School, Massachusetts General Hospital, Division of Infectious Diseases, Boston, USA. |
| 264 #1 - | |
| -- | Wallingford, Oxfordshire, UK : |
| -- | CABI, |
| -- | 2012. |
| 264 #4 - | |
| -- | ©2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (x, 357 pages) : |
| Other physical details | illustrations, charts. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in molecular and cellular microbiology ; |
| Volume number/sequential designation | 22 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc | This book, inclusive of 22 chapters, describes novel approaches currently used for antimicrobial drug discovery, focusing on agents for use against bacterial and fungal pathogens. Specific chapters discuss: (1) concepts relevant to drug resistance; (2) microbial mechanisms related to efflux pumps and studies on their potential inhibitors; (3) impact of multidrug tolerance of biofilms and persister cells; (4) bacterial quorum-sensing inhibition; (5) inhibition of the bacterial filamentous temperature-sensitive mutant Z (FtsZ); (6) antibacterial properties of lysostaphin; (7) strategies to identify modified ribosomally synthesized antimicrobials; (8) quantitative structure-activity relationship studies of novel antimicrobial peptides; (9) bacterial acetyl-CoA carboxylase and lipopolysacharide as drug targets for antibiotic development; (10) pathosystematic systems biology for the rational design of novel antifungal compounds; (11) specific animal models for novel antimicrobial discovery; and (12) new antimicrobial technology platforms such as antimicrobial photodynamic therapy and carbon nanotubes. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Emerging discovery strategies : an evolving necessity / Anthony R. Ball and George P. Tegos -- The antibiotic crisis / Arnold L. Demain and Jaroslav Spizek -- Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of escerichia coli and salmonella / Leonard Amaral ... [et al.] -- Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents / Sanjay M. Jachak ... [et al.] -- Fungal efflux-mediated resistance : from targets to inhibitors / Brian C. Monk ... [et al.] -- Vacuolar ATPase (V-ATPase) : a model proton pump for antifungal drug discovery -- Karlett J Parra -- Drug tolerance, persister cells and drug discovery / Kim Lewis -- Inhibition of quorum sensing as a novel antimicrobial strategy -- Gilles Brackman, Hans J. Nelis and Tom Coenye -- Filamentous temperature-sensitive mutant Z (FtsZ) protein as an antibacterial target / Jaroslaw M. Boberek ... [et al.] -- Lysostaphin : a silver bullet for staph / John F. Kokai-Kun -- Strategies to identify modified ribosomally synthesized antimicrobials -- Alan J. Marsh ... [et al.] -- QSAR based discovery of antimicrobial peptides active against multidrug resistant bacteria / Christopher D. Fjell ... [et al.] -- Acetyl-CoA carboxylase as a target for antibacterial development / Grover L. Waldrop -- Underexploited targets in LPS biogenenesis for the design of antibacterials / Laura Cipolla ... [et al.] -- Predicting and dissecting biomolecular interactions by information-driven docking / Panagiotis Kastritsis & Alexandre M.J.J Bonvin -- Anti-fungals and anti-fungal drug discovery / Richard Calderone ... [et al.] -- Pathosystematic studies and the rational design of antifungal interventions / Elaine M Bignell and Darius Armstrong-James -- In vivo high-throughput antimicrobial discovery screens utilizing caenorhabditis elegans as an alternative host / Jeffrey J. Coleman and Eleftherios Mylonakis -- Drosophila melanogaster as a versatile model for discovery of drugs effective against human microbe-induced infection and pathology / Yiorgos Apidianakis and Dimitrios P. Kontoyiannis -- Antimicrobial photosensitizers - harnessing the power of light to treat infections / Sulbha K Sharma, Tianhong Dai and Michael R Hamblin -- Nanoparticle platforms for antimicrobial therapy / David Trofa, Joshua D. Nosanchuk -- Antimicrobial activity of carbon nanotubes / Shaobin Liu, Yuan Chen. |
| 506 ## - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Access limited to subscribing institution. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Also available in print format. |
| 588 ## - | |
| -- | Title from PDF title page (viewed July 31, 2013). |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Anti-infective agents |
| General subdivision | Development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug resistance. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Anti-Infective Agents |
| General subdivision | pharmacology. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug Design. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Disease Models, Animal. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | High-Throughput Screening Assays |
| General subdivision | methods. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Photosensitizing Agents |
| General subdivision | pharmacology. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Prion, Viral, Bacterial and Fungal Pathogens of Humans, (New March 2000) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Animal Models of Human Diseases, (New March 2000) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Animal and in vitro Models for Pharmaceuticals, (New March 2000) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Non-drug Therapy and Prophylaxis of Humans, (New March 2000) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biosensors and Biological Nanotechnology, (New June 2002) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biochemistry and Physiology of Microorganisms, (New March 2000) |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Bacteria. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Fungi. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Acetyl-CoA carboxylase. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Animal models. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Antibacterial agents. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Antifungal agents. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Bacterial diseases. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biofilms. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Disease models. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug resistance. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug susceptibility. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug targets. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human diseases. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Laboratory animals. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Lipopolysaccharides. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Mycoses. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Peptide antibiotics. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Phototherapy. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Resistance mechanisms. |
| Source of heading or term | cabt |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Structure activity relationships. |
| Source of heading or term | cabt |
| 655 #0 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | VV210 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | VV400 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | VV450 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | VV710 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | WW900 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | ZZ394 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tegos, George, |
| Relator term | editor of compilation. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mylonakis, Eleftherios, |
| Relator term | editor of compilation. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | C.A.B. International, |
| Relator term | issuing body. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| Title | Antimicrobial drug discovery. |
| Place, publisher, and date of publication | Wallingford, Oxfordshire : CABI, c2012. |
| International Standard Book Number | 9781845939434 |
| Record control number | (DLC)2012001019 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in molecular and cellular microbiology ; |
| Volume number/sequential designation | 22. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://dx.doi.org/10.1079/9781845939434.0000">https://dx.doi.org/10.1079/9781845939434.0000</a> |
| Public note | Click here to access resource |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | E-BOOKS |
No items available.