G protein-coupled receptors : (Record no. 311780)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04559nam a22003738i 4500 |
| 001 - CONTROL NUMBER | |
| control field | CR9780511760334 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | UkCbUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200810130456.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m|||||o||d|||||||| |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr|||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100506s2011||||enk o ||1 0|eng|d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780511760334 (ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780521112086 (hardback) |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UkCbUP |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | UkCbUP |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP552.G16 |
| Item number | G1747 2011 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 572/.696 |
| Edition number | 22 |
| 245 00 - TITLE STATEMENT | |
| Title | G protein-coupled receptors : |
| Remainder of title | structure, signaling, and physiology / |
| Statement of responsibility, etc | edited by Sandra Siehler, Graeme Milligan. |
| 264 #1 - | |
| -- | Cambridge : |
| -- | Cambridge University Press, |
| -- | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xvi, 430 pages) : |
| Other physical details | digital, PDF file(s). |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Part I. Advances in GPCR Protein Research: 1. The evolution of the repertoire and structure of G protein-coupled receptors / Torsten Schöneberg, Kristin Schröck, Claudia Stäubert and Andreas Russ -- 2. Functional studies of isolated GPCR-G protein complexes in the membrane bilayer of lipoprotein particles / Adam J. Kuszak, Xiao Jie Yao, Sören G.F. Rasmussen, Brian K. Kobilka and Roger K. Sunahara -- Part II. Oligomerization of GPCRs: 3. GPCR-G protein fusions : use in functional dimerization analysis / Graeme Milligan -- 4. Time-resolved FRET approaches to study GPCR complexes / Jean Phillipe Pin, Damien Maurel, Laetitia Comps-Agrar, Carine Monnier, Marie-Laure Rives, Etienne Doumazane, Philippe Rondard, Thierry Durroux, Laurent Prézeau and Erin Trinquet -- 5. Signaling of dopamine receptor homo- and hetero-oligomers / Ahmed Hasbi, Brian F. O'Dowd and Susan R. George -- 6. Functional consequences of chemokine receptor dimerization / Mario Mellado, Carlos Martínez-A., and José Miguel Rodgríguez-Frade -- Part III. GPCR Signaling Features: 7. G protein functions identified using genetic mouse models / Stefan Offermanns -- 8. Kinetics of GPCR, G protein and effector activation / Peter Hein -- 9. RGS-RhoGEFs and other RGS multidomain proteins as effector molecules in GPCR-dependent and GPCR-independent cell signaling / José Vázquez-Prado and J. Silvio Gutkind -- 10. Adenylyl cyclase isoform-specific signaling of GPCRs / Karin F.K. Ejendal, Julie A. Przybyla, and Val J. Watts -- 11. G protein-independent and [beta] arrestin-dependent GPCR signaling / Zhongzhen Nie and Yehia Daaka -- 12. Assays to read GPCR modulation and signaling / Ralf Heilker and Michael Wolff -- Part IV. Ligand Pharmacology of GPCRs: 13. Quantifying allosteric ligand-receptor interactions / Ivan Toma Vranesic and Daniel Hoyer -- 14. 7TM receptor functional selectivity / Terry Kenakin -- Part V. Physiological Functions and Drug Targeting of GPCRs: 15. [Beta]-Adrenoreceptors in cardiovascular and respiratory diseases / Michele Ciccarelli, J. Kurt Chuprun and Walter J. Koch -- 16. Role of metabotropic glutamate receptors in CNS disorders / Richard M. O'Connor and John F. Cryan -- 17. S1P receptor agonists, a novel generation of immunosuppressants / Rósa Lopez Almagro, Gema Tarrasón, and Nuria Godessart -- 18. Wnt/Frizzled receptor signaling in osteoporosis / Georges Rawadi. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically β-adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | G proteins. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug delivery systems. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell receptors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cellular signal transduction. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Siehler, Sandra, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Milligan, Graeme, |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9780521112086 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1017/CBO9780511760334">https://doi.org/10.1017/CBO9780511760334</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | E-BOOKS |
No items available.