TY - BOOK AU - D'Mello,J.P.Felix ED - C.A.B. International, TI - Amino acids in human nutrition and health AV - QP561 .A4845 2012eb U1 - 612/.015756 23 PY - 2012/// CY - Wallingford, Oxfordshire, UK PB - CABI KW - Amino acids in human nutrition KW - Amino aicds KW - Metabolism KW - Amino Acids KW - metabolism KW - therapeutic use KW - Enzymes KW - Nutritional Physiological Phenomena KW - Animal Nutrition (Physiology) KW - Human Genetics and Molecular Medicine, (New June 2002) KW - Physiology of Human Nutrition KW - Molecular Biology and Molecular Genetics, (Discontinued March 2000, Reinstated and Revised June 2002) KW - Man KW - cabt KW - Amino acids KW - Biochemical markers KW - Biochemistry KW - Brain KW - Cognitive development KW - Health KW - Kinetics KW - Molecular genetics KW - Nutrition KW - Electronic books N1 - Includes bibliographical references and index; Glutamate dehydrogenase / T.J. Smith and C.A. Stanley -- Aminotransferases / M.E. Conway -- Arginase / R.W. Caldwell, S. Chandra and R.B. Caldwell -- Bypassing the endothelial l-arganine-nitric oxide pathway : effects of dietary nitrite and nitrate on cardiovascular function / P. Luedike, M. Kelm and T. Rassaf -- Histidine decarboxylase / E. Dere, O. Ambrée and A. Zlomuzica -- Glutamate decarboxylase / H. Ueno, Y. Inoue, S. Matsukawa and Y. Nakamura -- Glutaminase / J.M. Mateés, J.A. Segura, F.J. Alonso and J. Márquez -- D-serine and serine racemase in the retina / S.B. Smith, Y. Ha and V. Ganapathy -- Tryptophan hydroxylase / I. Winge, J. McKinney and J. Haavick -- Methionine metabolism / J.M. Mato, M.L. Martínez-Chantar and S.C. Lu -- Amino acid transport across each side of the blood-brain barrier / R.A. Hawkins, J.R. Viña, D.R. Peterson, R. O'Kane, A. Mokashi and I.A. Simpson -- Inter-organ fluxes of amino acids / M.C.G. van de Poll and C.H.C. Dejong -- Cellular adaption to amino acid availability : mechanisms involved in the regulation of gene expression / J. Averous, S. Lambert-Langlais, C, Chaveroux, L. Parry, V. Carraro, A.-C. Maurin, C. Jousse, A. Bruhat and P. Fafournoux -- Endogenous amino acids at the terminal ileum of the adult human / P.J. Moughan -- Metabolic availability of amino acids in food proteins : new methodology / C.L. Levesque, R. Elango and R.O. Ball -- Amino acid requirements : quantitative estimates / R.R. Pillai and A.V. Kurpad -- Amino acid supplements and muscular performance / T.A. Churchward-Venne, D.W.D. West and S.M. Phillips -- Amino acids in clinical and nutritional support : glutamine in Duchenne muscular dystrophy / E. Mok and R. Hankard -- Adverse effects / J.P.F. D'Mello -- The umami taste of glutamate / X. Li -- Homocysteine status : factors affecting and health risks / L.M. Steffen and B. Steffen -- Modified amino acid-based molecules : accumulation and health implications / S. Bengmark -- Phenylketonuria : newborn identification through to adulthood / R. Koch and K. Moseley -- Principles of rapid tryptophan depletion and its use in research on neuropsychiatric disorders / F.D. Zepf -- Excitatory amino acids in neurological and neurodegenerative disorders / G. Flores, J.V. Negrete-Díaz, M. Carrión, Y. Andrade-Talavera, S.A. Bello, T.S. Sihra and A. Rodríguez-Moreno -- Efficacy of L-DOPA therapy in Parkinson's Disease / G. Sahin and D. Kirik -- Amino acid profiles for diagnostic applications / T. Kimura, M. Takahashi, A. Imaizumi, Y. Noguchi and T. Ando -- Emergence of a new momentum / J.P.F. D'Mello; Access limited to subscribing institution; Also available in print format N2 - The chapters in this book are arranged within a thematic structure as indicated in the sections below. The first part pursues the theme of amino acid metabolism through the driving actions of the principal enzymes, emphasizing recent developments particularly with reference to localization, molecular genetics, biophysical characterization and regulation. Subsequent chapters will also demonstrate the changing facets of amino acid biochemistry. The competing actions of enzymes for critical substrates are also features of relevance in this section. A number of the enzymes under review here catalyse rate-limiting steps in important metabolic pathways, leading to synthesis of physiologically active intermediates and end products. There is scope for elaboration of the important pathways initiated by enzymes under review in this section. Part I has also been developed with the aim of underpinning subsequent chapters in this volume. Part II deals with important issues relating to whole-body amino acid dynamics, with a particular objective of supporting the chapters on nutrition and health that will follow. In this chapter, authors were encouraged to adopt an integrative approach to include their own expertise and that of others in their respective fields. A basic outline of metabolic pathways appears in Part I. The theme in this section centres around kinetics and regulation in broad-spectrum reviews incorporating innovative aspects of the relevant research. In other words, the concept of metabolic networking forms an underlying theme in this series of chapters. The chapters in part III cover a number of topical research investigations employing existing technologies to develop novel concepts or to underpin contemporary practices. At least four of the chapters in part IV focus on different amino acids associated with neurological issues and cognitive performance measures. The approach here is designed to reflect developments in epidemiology, monitoring, and clinical interventions in the various conditions under consideration in this section. The final section contains a plenary review designed to summarize the main findings in the foregoing chapters within an integrated account. The main theme centres around the concept of the emergence of a new momentum driving forward a progressive agenda in further elucidating the biochemical and health implications of amino acids UR - https://dx.doi.org/10.1079/9781845937980.0000 ER -