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Fetal nutrition and adult disease : programming of chronic disease through fetal exposure to undernutrition / edited by S.C. Langley-Evans, Division of Nutritional Biochemistry, School of Biosciences, University of Nottingham, UK.

Contributor(s): Material type: TextTextSeries: Frontiers in nutritional science ; no. 2.Publisher: Wallingford, Oxfordshire, UK : CABI Publishing, in association with The Nutrition Society, 2004Copyright date: 2004Description: 1 online resource (x, 433 pages) : illustrations, chartsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
Subject(s): Genre/Form: Additional physical formats: Print version:: Fetal nutrition and adult disease.DDC classification:
  • 616/.044 23
LOC classification:
  • RB156 .F48 2004eb
Online resources: Also available in print format.
Contents:
Fetal Programming of Adult Disease : an Overview / Simon C. Langley-Evans -- Nutritional Basis for the Fetal Origins of Adult Disease / Jane Harding -- Intrauterine Hypoxaemia and Cardiovascular Development / Dino A. Giussani and David S. Gardner -- Epidemiology of the Fetal Origins of Adult Disease : Cohort Studies of Birthweight and Cardiovascular Disease / Janet Rich-Edwards -- Early-life Origins of Adult Disease : is There Really an Association Between Birthweight and Chronic Disease Risk? / Rachel Huxley -- Experimental Models of Hypertension and Cardiovascular Disease / Simon C. Langley-Evans -- Associations between Fetal and Infant Growth and Non-insulin-dependent Diabetes / Simon C. Langley-Evans -- Programming of Diabetes : Experimental Models / Brigitte Reusens, Luise Kalbe and Claude Remacle -- Birthweight and the Development of Overweight and Obesity / Aryeh D. Stein -- Maternal Nutrition in Pregnancy and Adiposity in Offspring / Bernhard H. Breier, Stefan O. Krechowec and Mark H. Vickers -- Renal Disease and Fetal Undernutrition / Lori L. Woods -- Perinatal Determinants of Atopic Disease / Kitaw Demissie, Katherine D. Chung and Bijal A. Balasubramanian -- Fetal Programming of Immune Function / Thomas W. McDade and Christopher W. Kuzawa -- Programming in the Pre-implantation Embryo / Lorraine E. Young, William D. Rees and Kevin D. Sinclair -- Endocrine Responses to Fetal Undernutrition : the Growth Hormone-Insulin-like Growth Factor Axis / Michael E. Symonds, David S. Gardner, Sarah Pearce and Terence Stephenson -- Impact of Intrauterine Exposure to Glucocorticoids upon Fetal Development and Adult Pathophysiology / Amanda J. Drake and Jonathan R. Seckl.
Abstract: This book aims to paint a broad picture of current understanding of fetal programming. The volume presents a range of epidemiological data demonstrating links between events in fetal life and the development of cardiovascular disease, non-insulin-dependent diabetes, obesity and disorders of the immune system. The book is divided into three parts: programming the fetus (Part I), programming human disease (part II) and biological basis of nutritional programming (part III). Part I sets out the basic principles of programming and considers the potential contribution of undernutrition and other insults during critical phases of embryonic and fetal development, to abnormal physiology and disease processes in later life. Part II provides the core of the book and shows how suggestive epidemiological evidence for an association between characteristics at birth and later disease is replicated in experimental model. This part presents data that question the birthweight-disease association, highlighting the importance of well-designed experimental studies. The final part of the book sets out current ideas about the interrelationships of maternal nutrition, placental function and fetal endocrinology and looks at how early nutrient-gene interactions may exert permanent influences on health and well-being of an individual.
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This book aims to paint a broad picture of current understanding of fetal programming. The volume presents a range of epidemiological data demonstrating links between events in fetal life and the development of cardiovascular disease, non-insulin-dependent diabetes, obesity and disorders of the immune system. The book is divided into three parts: programming the fetus (Part I), programming human disease (part II) and biological basis of nutritional programming (part III). Part I sets out the basic principles of programming and considers the potential contribution of undernutrition and other insults during critical phases of embryonic and fetal development, to abnormal physiology and disease processes in later life. Part II provides the core of the book and shows how suggestive epidemiological evidence for an association between characteristics at birth and later disease is replicated in experimental model. This part presents data that question the birthweight-disease association, highlighting the importance of well-designed experimental studies. The final part of the book sets out current ideas about the interrelationships of maternal nutrition, placental function and fetal endocrinology and looks at how early nutrient-gene interactions may exert permanent influences on health and well-being of an individual.

Includes bibliographical references and index.

Fetal Programming of Adult Disease : an Overview / Simon C. Langley-Evans -- Nutritional Basis for the Fetal Origins of Adult Disease / Jane Harding -- Intrauterine Hypoxaemia and Cardiovascular Development / Dino A. Giussani and David S. Gardner -- Epidemiology of the Fetal Origins of Adult Disease : Cohort Studies of Birthweight and Cardiovascular Disease / Janet Rich-Edwards -- Early-life Origins of Adult Disease : is There Really an Association Between Birthweight and Chronic Disease Risk? / Rachel Huxley -- Experimental Models of Hypertension and Cardiovascular Disease / Simon C. Langley-Evans -- Associations between Fetal and Infant Growth and Non-insulin-dependent Diabetes / Simon C. Langley-Evans -- Programming of Diabetes : Experimental Models / Brigitte Reusens, Luise Kalbe and Claude Remacle -- Birthweight and the Development of Overweight and Obesity / Aryeh D. Stein -- Maternal Nutrition in Pregnancy and Adiposity in Offspring / Bernhard H. Breier, Stefan O. Krechowec and Mark H. Vickers -- Renal Disease and Fetal Undernutrition / Lori L. Woods -- Perinatal Determinants of Atopic Disease / Kitaw Demissie, Katherine D. Chung and Bijal A. Balasubramanian -- Fetal Programming of Immune Function / Thomas W. McDade and Christopher W. Kuzawa -- Programming in the Pre-implantation Embryo / Lorraine E. Young, William D. Rees and Kevin D. Sinclair -- Endocrine Responses to Fetal Undernutrition : the Growth Hormone-Insulin-like Growth Factor Axis / Michael E. Symonds, David S. Gardner, Sarah Pearce and Terence Stephenson -- Impact of Intrauterine Exposure to Glucocorticoids upon Fetal Development and Adult Pathophysiology / Amanda J. Drake and Jonathan R. Seckl.

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Also available in print format.

Title from PDF title page (viewed August 15, 2013).

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